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Fast Dual-Regularized Autoencoder for Sparse Biological Data

Poleksic, Aleksandar

arXiv.org Artificial Intelligence

Algorithms for sparse matrix completion are used in recommender systems to predict user preferences to items such as news, movies, or songs [1]. The same methods can be successfully applied in other fields, for instance in systems biology to predict gene-disease associations or in computational systems pharmacology to predict adverse drug reactions [2] and to repurpose FDA approved drugs [3]. Matrix completion is the task of filling out missing entries in an observed sparse matrix. A low rank solution to matrix completion problem can be obtained via matrix factorization, a technique that approximates the input sparse matrix as a product of two lower dimensional matrices of users' and items' latent vectors [4]. Despite efforts to develop more sophisticated techniques, such as the methods based on artificial neural networks [5], matrix factorization remains the method of choice in recommender systems due to its efficiency and high accuracy [6].


The Morning After: Apple's Mac and Google's Pixel events, previewed

Engadget

Apple's second fall product event kicks off later today at 1 PM ET. We've laid out what to expect, but it's not the only big tech event week. Spare a thought for some of our staff, who will go straight from Apple reportage into Google. Yep, Tuesday October 19th is Google's Pixel 6 event. While we know what the phone will look like -- and some of its specifications -- expect to see some software surprises.


A group of new astronauts join NASA under the Artemis program and could be the first to step on Mars

Daily Mail - Science & tech

It has been more than two years in the making, but 13 new astronauts have finally joined NASA under the mission that will bring the first female to the moon -and some may be the first humans to step on Mars. The candidates, who have been training since 2017, participated in the first public graduation ceremony for astronauts on Friday at the American space Agency's Johnson Space Center in Houston. The group includes six women and seven men, two of them were Canadian Space Agency (CSA) astronauts, and all were chosen from record-setting pool of more than 18,000 applicants. During the ceremony, each of the bright-eyed graduates were given a silver pin that symbolizes the Mercury 7 – NASA's first astronaut group that was selected in 1959. They will then be awarded a gold pin once they completed their first spaceflights.